二十世纪三十年代的上海，姚小蝶、露露、凤萍、莲西四个女孩子因为同样爱好歌唱走到一起。姚小蝶自幼被人遗弃，她一心想手刃仇人陆汉替父报仇。这天在乘车时，姚小蝶意外结识演奏萨克斯的青年沈家豪。此后两人因为演出频频接触，慢慢地两人滋生出别样情愫。然而姚小蝶始终不忘杀父之仇，她忍痛放弃跟沈家豪的感情。此后，在经历一些风风雨雨后，姚小蝶才发现误会陆汉是仇人，在国家受外敌入侵遭日寇践踏时，姚小蝶放下私人恩怨和陆汉共同抗日。最后还在陆汉帮助下找到生母并相认。凤萍则遇人不淑爱上了一个好赌的男人，凤萍生下儿子希望后，最后跟丈夫一起客死他乡让人唏嘘不已。莲西结识了青年逸天，最后她勇敢跟随逸天成为革命青年。露露的命运也同样一波三折，她染上重疾，原以为必死无疑，她准备自杀一了百了。最后才发现她患的的不是绝症，露露死里逃生重新燃起生活希望，最后还得以嫁入豪门。四个姐妹命运各不相同，唯一不变的是她们之间的情意

In Shanghai in the 1930s, four girls, Yao Xiaodie, Lulu, Fengping, and Lianxi came to the world because of the same love of singing. Together. Yao Xiaodie was abandoned since she was a child, and she wanted to avenge her father by killing her enemy Lu Han. While riding the car that day, Yao Xiaodi accidentally met Shen Jiahao, a young man who played the saxophone. Since then, the two have been in frequent contact because of performances, and gradually a different kind of affection has developed between the two. However, Yao Xiaodi never forgot the revenge of killing her father, so she reluctantly gave up her relationship with Shen Jiahao. Afterwards, after going through some ups and downs, Yao Xiaodi realized that she misunderstood Lu Han as an enemy. When the country was invaded by foreign enemies and trampled by Japanese invaders, Yao Xiaodi put aside her personal grievances and joined Lu Han in fighting against Japan. Finally, with the help of Lu Han, they found their biological mother and recognized each other. Fengping, on the other hand, fell in love with a man who was fond of gambling. After Fengping gave birth to her son Hope, she finally died in a foreign country with her husband, which is embarrassing. Lianxi got acquainted with the young man Yitian, and finally she bravely followed Yitian to become a revolutionary youth. Lulu's fate was also full of twists and turns. She contracted a serious illness and thought she would die, so she planned to commit suicide to kill everything. It was finally discovered that she was not terminally ill, and Lulu's narrow escape rekindled her hope of life, and finally she was able to marry into a wealthy family. The destinies of the four sisters are different, the only constant is the affection between them