讲述1943年10月常德被日军从由沙市，岳阳渡江围住，守城的是国军57师代号“虎贲”，他势必与城共存亡，师长余程万（吕良伟饰）心里预料这场战争可能凶多吉少，百姓全部撤退，常德就变成一座“孤城”，连长冯葆华（袁文康饰）坚持不懈在前线誓死守护，今天本该是他和爱人婉清（安以轩饰）的新婚之夜，却因为这场战争不得不上战场，思念丈夫心切，婉清因担心便跟随其后，在战地当护士救死扶伤，智勇双全的冯葆华在16岁的民兵二虎（谢孟虎饰）心中视为榜样，舍己为人……此时二虎狼狈不堪的在死人堆里大声重复着冯葆华说的话，而他们拼命抵抗，在这座攻而不破的孤城中，日军怎么也不会想到，仅有不过百余个士兵在此坚守！此时一身令下杀身成仁，不到最后一刻绝不撤退，进退两难下，余程万人的绝笔手书手书绝笔整齐披挂，率众士兵突围…

In October 1943, Changde was besieged by the Japanese army from Youshashi and Yueyang across the river. He is bound to live and die with the city. The division commander Yu Chengwan (played by Lu Liangwei) predicted in his heart that this war may be more or less ominous, and the people will all retreat, and Changde will become an "isolated city". Guardian, today was supposed to be the wedding night of him and his lover Wanqing (played by An Yixuan), but because of this war, he had to go to the battlefield. He missed her husband so much, Wanqing followed because of worry, and worked as a nurse on the battlefield to save lives and heal the wounded. Feng Baohua, who has both abilities, is regarded as a role model in the heart of the 16-year-old militiaman Erhu (Xie Menghu), who sacrifices himself for others... At this time, Erhu repeats Feng Baohua's words loudly in the crowd of dead people, and they resist desperately. In the unbreakable isolated city, the Japanese army would never have imagined that there were only a few hundred soldiers standing here! At this time, he was ordered to kill himself and become benevolent, and he would not retreat until the last moment. In a dilemma, Yu Chengwan's last handwriting and last handwriting were neatly put on, leading the soldiers to break through..