肖瀚、王琨、刘磊、汤怀、艾木是大学室友，虽是铁哥们，但是活法却各不相同。王琨年近四十一直单身，每天跑步幻想着能邂逅一见钟情，不料刚遇见梦中情人便心梗而死。有女友的刘磊和别的女人约会开房，被女友梁莹带着肖瀚、沈红夫妇前去捉奸，上演出一出裸奔闹剧。现世安稳的肖瀚觉得生活平淡无味，开始感叹人生。偶然在地下停车场邂逅了一位红裙女子，红裙女子的妖娆性感引得肖瀚春心荡漾，不由一路追随，心脏监护手表因而发出报警，引来妻子的关心电话，肖瀚只得解释为跟同事常剑抢车位。等到肖瀚发现红裙女子是公司请来的模特后，心猿意马的他开始借着工作之便接近红裙女，幻想着再次体验心跳的刺激。但事与愿违，他的几次行动都阴差阳错地失败了，蠢蠢欲动的他只好求助自己的铁哥们帮忙，而在这一系列神操作之下，艾木也对肖瀚的女上司玛丽莲一见钟情……各种搞笑一路上演…

Xiao Han, Wang Kun, Liu Lei, Tang Huai, and Ai Mu are college roommates. Although they are close buddies, they live in different ways. Wang Kun has been single for almost 40 years. He runs every day and fantasizes about meeting love at first sight. Unexpectedly, he died of a heart attack just after meeting the lover of his dreams. Liu Lei, who has a girlfriend, has a date with another woman, and his girlfriend Liang Ying takes Xiao Han and Shen Hong to catch the rape, and staged a streaking farce. Xiao Han, who is stable in this world, feels that life is dull and boring, and begins to lament life. Accidentally ran into a woman in a red dress in the underground parking lot. The enchanting sexiness of the woman in the red dress attracted Xiao Hanchun's heart, and he couldn't help but follow him all the way. The heart monitoring watch then issued an alarm, which attracted a concern call from his wife. Chang Jian grabs the parking space. When Xiao Han found out that the woman in the red dress was a model hired by the company, he was distracted and began to approach the woman in the red dress through work, imagining that he would experience the thrill of the heartbeat again. But things backfired. Several of his actions failed by accident, and he had no choice but to ask his best friend for help. Under this series of magical manipulations, Ai Mu also fell in love with Xiao Han's female boss Marilyn at first sight. ... All kinds of jokes are staged along the way..