麦考尔曾经是一名中情局的秘密特工，一个冷酷的职业杀手，但是他已经隐姓埋名多年，成为了一名司机。政府探员苏珊是他唯一的朋友，两人的感情就像姐弟那样，因此苏珊是唯一知道麦考尔还活着的人，两人一直保持联系。这天，苏珊被上级召唤到布鲁塞尔，调查一名特工的自杀案件，但是也因此和麦考尔失去了联系，敏锐的他认为苏珊已经被人杀害。确定苏珊已死，麦考尔想要去调查苏珊的死亡真相，他不得不重出江湖找到当年的大党约克。经过他们的调查发现，他们曾经的同事和这个案件有千丝万缕的联系，苏珊死亡也是因为调查到特工之死并非自杀。曾经的同事变成了自由杀手，他们的任务就是杀死苏珊，因此麦考尔不得不与曾经的朋友和同事反目成仇

McCall was once a secret agent of the CIA, a ruthless professional killer, but he has been incognito for many years and became a driver. Government agent Susan is his only friend, and the relationship between the two is like siblings, so Susan is the only person who knows that McCall is still alive, and the two have kept in touch. On this day, Susan was summoned to Brussels by her superiors to investigate the suicide of an agent, but she lost contact with McCall because of this. He was keenly aware that Susan had been killed. After confirming that Susan was dead, McCall wanted to investigate the truth of Susan's death, so he had to go back to find York, the big party back then. After their investigation, they found that their former colleagues were inextricably linked to this case, and Susan's death was also due to the investigation that the agent's death was not a suicide. Once colleagues turned freelance killers, their mission is to kill Susan, so McCall has to turn against his former friends and colleagues