本世纪初基因实验基地遭到恐怖分子袭击，一些特殊病毒泄露出去侵害了人类的大脑。人类大脑也因为感染特殊病毒发生变异，人类因此可以看到怪灵，一种幽灵般的存在。就在特殊病毒泄露事件发生前后一批孩子出生，这部分孩子中就有一些能跟怪灵战斗。为此防卫省为给中小学孩子们解决怪灵问题，专门成立脑功能异常对策室。一条晴彦就是这类学院塞亚学院高中部的一名学生。晴彦从小阅读过大量书籍，有相当丰富的知识储备，他能够凭借掌握的知识攻克一个又一个难题。他随身携带一个手提包，手提包里装着他的写生本。晴彦能够将画好的怪灵召唤出来参加战斗，也可以将战斗中的怪灵通过绘画进行封印。他利用自己的技能跟前辈神舞、泉玲奈、还有水濑等人一起投入到对付怪灵的作战中，然而有些真相还有待于他们去揭秘…

At the beginning of this century, the genetic experiment base was attacked by terrorists, and some special viruses leaked and attacked the human brain. The human brain is also mutated due to infection with a special virus, so humans can see ghosts, a ghostly existence. A group of children were born just before and after the special virus leak, and some of these children could fight monsters. For this reason, the Ministry of Defense has set up a countermeasure room for abnormal brain function in order to solve the problem of ghosts for elementary and middle school children. Haruhiko Ichijo is a student in the high school of Seiya Academy of this kind of school. Haruhiko has read a lot of books since he was a child, and has a considerable reserve of knowledge. With the knowledge he has mastered, he can overcome one problem after another. He carried a handbag with him, in which was his sketchbook. Haruhiko can summon the painted monsters to participate in the battle, and can also seal the monsters in battle through painting. He used his own skills to participate in the battle against monsters with his seniors Kamui, Izumi Rena, and Minase, but some truths have yet to be revealed by them..